A saponin-based nanoparticle adjuvant
In late 2014 Brenntag Biosector entered a strategic alliance with the Swedish biotech company MoreinX. This allowed Brenntag Biosector to further develop and later put into production a series of immunostimulating nanoparticles, referred to as G3 particles.
These particles are composed of Quillaja saponin and cholesterol and are smaller than traditional ISCOMs and will be commercialized by Brenntag under the registered trade name of NanoQuil®.
The first data from the testing of these nanoparticles have already been published:
Novel G3/DT adjuvant promotes the induction of protective T cells responses after vaccination with a seasonal trivalent inactivated split-virion influenza vaccine. [Van de Sandt et al. (2014). VACCINE 32 : 5614-5623]